Since our inception as a “research and innovation” organization in 2012, we have been on a relentless pursuit to overcome gut-mediated diseases. As a biotech company, we aspire to design a future where patients suffering from chronic kidney disease (CKD), end-stage renal disease (ESRD), and liver cirrhosis can look forward to healthier tomorrows.
At the intersection of biotech innovation and technology, our therapeutic approach revolves around synbiotics, enzobiotics, and enzotien research. This forms the cornerstone of future medical research, fostering a highly personalized healthcare paradigm that takes into account each individual’s unique hidden metabolic signature. With a dedicated vision to uncover these concealed metabolic markers within the intricate network of the gut’s 100 trillion microbiota, we recognize the profound impact of microbiota dysbiosis on quality of life and its role in various ailments. Our unwavering commitment drives us to pioneer evidence-based research, aimed at delivering tailored therapeutic solutions.
Over the last decade, we have been at the forefront of investigating the Gut-Kidney Axis, Gut-Brain Axis, and the Gut-Liver Axis, recognizing the pivotal role these play in understanding and managing gut-related diseases.
Conceptualisation
Our ideating phase involves dedicated efforts in developing unique solutions to bolster healthcare for CKD and ESRD patients
Product Development
Here is where we transform concepts into tangible products through research and design
Validation
Our products undergo thorough testing and verification to ensure superior quality, safety, and efficacy
Phase II
We conduct controlled studies to assess product effectiveness and safety in a larger group of participants
Phase III
We gather additional data on product efficacy and side effects through a larger-scale clinical trial and comparing them with best currently available treatment options
Phase IV
We then monitor the product’s performance and safety in real-world conditions after it is approved
Manufacturing
Large-scale production and quality control processes are then done to ensure consistent and reliable product manufacturing
Derived from the Greek “probiotic,” meaning “for life,” probiotics are live microorganisms that benefit health when consumed in the right amounts. Prebiotics, on the other hand, support probiotic bacteria growth in the body. Synbiotics, a combination of both, play a therapeutic role in maintaining a healthy gastrointestinal tract. Notably, they reduce inflammatory markers like HSCRP, IL-6, and TNF. This makes them effective in managing conditions like uremic pruritus and Kyrle’s disease (KD), particularly in the context of chronic kidney disease (CKD) and uraemia. Synbiotics thus significantly enhance well-being through their profound gut health impact.
Enzobiotics, a unique fusion of synbiotics and proteolytic enzymes, offer a promising solution in the context of chronic kidney disease (CKD). These specialized compounds have the capacity to regulate the balance of intestinal microbiota while enhancing protein absorption in the small intestine. This dual action holds the potential to thwart the formation of protein-bound uremic toxins (PBUTs) generated through intestinal microbial metabolism of aromatic amino acids. By addressing dysbiosis and potentially preventing the generation of PBUTs like IS and PCS, which are known to contribute to CKD progression and mortality, enzobiotics can significantly improve the quality of life for CKD patients.
Enzotien, a unique blend of proteolytic enzymes and low-dose protein supplements, effectively tackles protein energy malnutrition in economically disadvantaged end-stage renal disease (ESRD) patients. By enhancing protein breakdown and assimilation, Enzotien matches the nutritional and anti-inflammatory benefits of high-dose protein intake. This innovative combination excels at facilitating the efficient breakdown, assimilation, and absorption of proteins with an impressive PDCAAS value >1. This innovative approach can serve as a viable, cost-effective solution in resource-limited settings, promising to alleviate protein energy malnutrition and accelerate recovery, potentially shortening the healing process by 18 months for ESRD patients undergoing hemodialysis.